MRXS viewer

3DHISTECH CaseViewer: Download, Mac Version and Alternatives

CaseViewer was 3DHISTECH's viewer for MRXS slides until June 2021, when SlideViewer was released as its successor. On Windows, the program to download today is SlideViewer. On a Mac, 3DHISTECH still offers CaseViewer 2.2.1, but it only shows slides from a CaseCenter or SlideCenter server and cannot open an MRXS slide stored on the Mac. To open MRXS on a Mac, SlideScope opens the slide from your own disk on macOS and Windows, and QuPath is free.

macOS and WindowsMRXS, SVS, NDPI, CZI, ND2Slides stay on your computer

Where to download CaseViewer, and what replaced it

3DHISTECH announced SlideViewer on 11 June 2021 as the successor of CaseViewer. Its software downloads page listed these viewers when we checked on 13 November 2026:

DownloadRuns onWhat 3DHISTECH says
SlideViewer 2.9.0WindowsCompatible with Windows 10 and 11
CaseViewer 2.2.1macOSOptimized for macOS 10.13 or newer; designed to work exclusively with CaseCenter or SlideCenter
CaseViewer 2.3, German language versionWindowsA localized version for German-speaking users
Pannoramic Viewer 1.15.4WindowsLegacy, no longer supported

No other CaseViewer installer for Windows was listed. If you are looking for CaseViewer on a Windows PC, install SlideViewer: it is free, opens MRXS slides, and is the Windows viewer 3DHISTECH lists today. Our SlideViewer page has the download steps and system requirements.

Download from 3DHISTECH itself. Third-party download sites that still offer old CaseViewer installers are not the vendor's source.

CaseViewer for Mac: what it can and cannot open

3DHISTECH's page on CaseViewer for Mac is direct about its limits. Only CaseViewer 2.2.1 runs on a Mac; every other CaseViewer and SlideViewer version is for Windows only. The Mac version is meant for slides on a CaseCenter or SlideCenter server, so a Mac user who receives slides on a USB stick or through a file sharing service cannot open them with CaseViewer.

3DHISTECH names three ways forward for Mac users:

  1. Connect to the CaseCenter or SlideCenter at your institution, with a login from its administrator.
  2. Look at demo slides on 3DHISTECH's demo site.
  3. For expert users: run Windows 10 in a virtual machine on the Mac and use the Windows viewer there.

If the slide is a file on your Mac and you do not want a Windows virtual machine, you need a different viewer. The steps below use SlideScope; QuPath is the free alternative.

How to open an MRXS slide on a Mac or Windows with SlideScope

  1. Install SlideScope for macOS 14 or later (Apple silicon or Intel) or for Windows 10 or 11. The download is free, and the built-in sample library is free with every tool; opening your own images needs a subscription.
  2. Copy the complete slide to a local disk: the .mrxs file and the folder with the same name next to it, which holds Slidedat.ini, the index file and the Data*.dat files. Do not rename either one.
  3. Open the .mrxs file in SlideScope, or drag it into the viewer. Open the .mrxs, not the folder or a .dat file.
  4. Pan and zoom through the slide, use the overview navigator, check the slide metadata, and make calibrated measurements or annotations.

If only the .mrxs file arrives, the slide cannot open: it is a small index, and the pixels live in the data folder. SlideScope checks for that folder and tells you what is missing. MRXS slides open from local storage only. Full limits are on the file compatibility page and in the MRXS guide.

CaseViewer for Mac, SlideViewer and SlideScope compared

 CaseViewer 2.2.1 for MacSlideViewer 2.9.0SlideScope
PlatformsmacOS 10.13 or newerWindows 10 and 11macOS 14 or later (Apple silicon and Intel), Windows 10/11
CostDirect download on 3DHISTECH's pageFree downloadPaid: free download and free sample library, then a subscription for your own images (plans)
MRXS slide on your own diskNo: server slides onlyYesYes, from local storage
CaseCenter or SlideCenter serverYesSlideCenter, per 3DHISTECHNo
How MRXS is read3DHISTECH's own software3DHISTECH's own softwareThrough the open-source OpenSlide library
Other slide formatsNot statedDICOM, SVS, Roche TIF and moreSVS, NDPI, SCN, BIF, DICOM, OME-TIFF, CZI, ND2 and more

CaseViewer and SlideViewer facts come from 3DHISTECH's own pages, checked on 13 November 2026; see the sources below.

When 3DHISTECH's own viewer is the better choice

If your slides live on your institution's CaseCenter or SlideCenter, CaseViewer for Mac is 3DHISTECH's own tool for exactly that job. If you are on Windows, SlideViewer is free and is built by the company that makes the format. It is also the safer choice for multichannel fluorescence MRXS scans: SlideScope reads MRXS through OpenSlide, and QuPath's format documentation notes that OpenSlide's MRXS support is limited to 2D, 8-bit RGB slides without JPEG-XR compression. If you need a free viewer on a Mac for a brightfield slide on your disk, QuPath is free and open source. SlideScope fits when you want to open that slide on a Mac without a server or a virtual machine, measure and annotate it, and use the same viewer for your other formats.

CaseViewer and MRXS questions

Where can I download 3DHISTECH CaseViewer?

3DHISTECH's software downloads page lists CaseViewer 2.2.1 for macOS and a German language version of CaseViewer 2.3, checked on 13 November 2026. For Windows it lists SlideViewer 2.9.0, the successor to CaseViewer, which is the one to install.

Is CaseViewer the same as SlideViewer?

SlideViewer is its successor. 3DHISTECH announced SlideViewer on 11 June 2021 as the successor of its CaseViewer slide viewing application.

Is there a CaseViewer for Mac?

Yes, CaseViewer 2.2.1, but it is intended for slides on a CaseCenter or SlideCenter server. 3DHISTECH states that Mac users who receive slides on a USB stick or through a file sharing service cannot open them with CaseViewer.

How do I open an MRXS file on a Mac?

Use a macOS viewer that reads MRXS from your disk, such as SlideScope (macOS 14 or later, Apple silicon and Intel) or the free, open-source QuPath. Keep the .mrxs file and its data folder together.

Why won't my MRXS file open?

Almost always because only the .mrxs file was copied. An MRXS slide is the .mrxs file plus a folder with the same name next to it, holding Slidedat.ini, the index file and the Data*.dat files with the pixels. Copy both, keep their names unchanged, and open the .mrxs again.

Is SlideScope free?

No. SlideScope is a paid app. The download and the built-in sample library are free, with every tool, and the app checks for free whether your own files open. Opening your own images needs a subscription; current prices are on the plans page.

Does SlideScope upload my slides?

No. SlideScope reads MRXS slides from your own disk, and MRXS slides can only be opened from local storage. Optional features such as AI Analysis or shared links are separate, and only run when you choose to use them.

Sources and non-affiliation note

SlideScope is independent and is not affiliated with, endorsed by, or sponsored by 3DHISTECH. CaseViewer and SlideViewer are names of 3DHISTECH products and are used here only to describe comparison and alternative search intent. Facts about CaseViewer and SlideViewer were taken from 3DHISTECH's own pages on 13 November 2026:

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