MRXS viewer

3DHISTECH SlideViewer: Download, Mac Version and Alternatives

SlideViewer is 3DHISTECH's free viewer for its MRXS slides, and the successor to CaseViewer. On Windows 10 or 11, download it from 3DHISTECH. There is no SlideViewer for Mac, and the old CaseViewer for Mac cannot open slides stored on the Mac itself. To open MRXS on a Mac, or to use one viewer for MRXS alongside SVS, CZI, ND2 and DICOM, SlideScope opens MRXS slides locally on macOS and Windows, with nothing uploaded.

macOS and WindowsMRXS, SVS, NDPI, CZI, ND2Slides stay on your computer

Where to download SlideViewer (Windows)

  1. Go to 3DHISTECH's software downloads page. SlideViewer 2.9.0 was the version offered on 8 October 2026.
  2. Check your PC: 3DHISTECH lists Windows 10 22H2 Professional 64-bit or newer (the download page says Windows 10 and 11), 4 GB of RAM and a 1320 × 720 screen.
  3. Install it and open the .mrxs file, with its data folder next to it.

Download it from 3DHISTECH itself. Searching for "slideviewer download" also turns up an unrelated open-source project and third-party download sites with the same name.

On a Mac? 3DHISTECH's only Mac viewer is CaseViewer 2.2.1, and 3DHISTECH states that it cannot open slides copied to the Mac from a USB drive or a file-sharing service; it only connects to a CaseCenter or SlideCenter server. For slides on your own disk, use the steps below.

How to open an MRXS slide on a Mac or Windows with SlideScope

  1. Download SlideScope for macOS 14 or later (Apple Silicon or Intel) or Windows 10/11 and install it. The built-in sample library needs no account.
  2. Copy the complete slide to a local disk: the .mrxs file and the folder with the same name next to it, which holds Slidedat.ini, the index file (usually Index.dat) and the Data*.dat files. Do not rename either one.
  3. Open the .mrxs file in SlideScope, or drag it into the viewer. Open the .mrxs, not the folder or a .dat file.
  4. Pan and zoom through the slide, use the overview navigator to move around, check the slide metadata, and make calibrated measurements or annotations.

If only the .mrxs file arrives, the slide cannot open: it is a small index, and the pixels live in the data folder. SlideScope checks for that folder and tells you what is missing. MRXS slides must be opened from local storage; they are not supported through remote links. Full limits are on the file compatibility page and in the MRXS guide.

SlideViewer and SlideScope compared

 3DHISTECH SlideViewerSlideScope
PlatformsWindows 10 22H2 Professional 64-bit or newer. No macOS version listedmacOS 14 or later (Apple Silicon and Intel), Windows 10/11
PriceFree downloadFree samples with every tool, then a subscription from $29.99/month for your own images (pricing)
Slide formatsMRXS, DICOM, SVS, Roche TIF “and more”MRXS, SVS, NDPI, SCN, BIF, DICOM, TIFF and OME-TIFF, plus CZI, ND2, LIF and IMS microscopy files
How MRXS is read3DHISTECH's own viewer for its formatThrough the open-source OpenSlide library
Where slides are viewedDesktop applicationDesktop application; MRXS opens from local storage only
Annotations and measurementAnnotations and measurement toolsCalibrated measurements and saved annotations
Other listed tools3D Z-stack viewing, polarization imaging, TMA core toolsOverview navigator, metadata panel, brightness, contrast and channel controls

SlideViewer facts come from 3DHISTECH's own pages, checked on 8 October 2026; see the sources below.

When SlideViewer is still the better choice

If you are on Windows and your slides all come from 3DHISTECH scanners, SlideViewer is free and built by the company that makes the format, with tools such as TMA core marking and Z-stack viewing that SlideScope does not try to copy. It is also the safer choice for multichannel fluorescence MRXS scans: SlideScope reads MRXS through OpenSlide, and QuPath's format documentation notes that OpenSlide's MRXS support is limited to 2D, 8-bit RGB slides without JPEG-XR compression. The brightfield slides in our format benchmark all opened. If you need a free viewer on a Mac, QuPath is free and open source. For a wider look, see the whole slide image viewer comparison.

SlideViewer and MRXS questions

Where can I download 3DHISTECH SlideViewer?

From 3DHISTECH's software downloads page on its partners portal, which offered SlideViewer 2.9.0 for Windows 10 and 11 when we checked on 8 October 2026. SlideViewer is free; download it from 3DHISTECH rather than a third-party download site, which may carry an unrelated program with the same name.

Is there a 3DHISTECH SlideViewer for Mac?

No. SlideViewer runs on Windows only (3DHISTECH lists Windows 10 22H2 Professional 64-bit or newer). The only Mac relative is the older CaseViewer 2.2.1, which 3DHISTECH says cannot open slides copied to the Mac: it only shows slides from a CaseCenter or SlideCenter server. To open MRXS files on a Mac, use a macOS viewer that reads MRXS, such as SlideScope (macOS 14 or later, Apple Silicon and Intel) or the free, open-source QuPath.

Why won't my MRXS file open?

Almost always because only the .mrxs file was copied. An MRXS slide is the .mrxs file plus a folder with the same name next to it, holding Slidedat.ini, the index file (usually Index.dat) and the Data*.dat files with the pixels. Copy the .mrxs and that folder together, keep their names unchanged, and open the .mrxs again.

Can I open MRXS files without registering?

When we checked on 8 October 2026, 3DHISTECH offered SlideViewer 2.9.0 as a direct download on its partners portal. SlideScope also downloads without an account, and its built-in sample library works without one. QuPath is free and needs no account.

Is SlideScope free?

SlideScope is a paid app with a free sample library (every tool); your own images need a subscription from $29.99/month.

Explore the built-in sample library free, with every tool. Opening your own images needs a subscription: $29.99/month, billed when you subscribe (PayPal or card), and you can cancel anytime from your account. Annual billing is available at $299.99/year, which works out to about two months free.

Does SlideScope upload my slides?

No. SlideScope reads MRXS slides from your own disk, and MRXS slides can only be opened from local storage. Optional features such as AI Analysis or shared links are separate, and only run when you choose to use them.

Sources and non-affiliation note

SlideScope is independent and is not affiliated with, endorsed by, or sponsored by 3DHISTECH. SlideViewer and CaseViewer are names of 3DHISTECH products and are used here only to describe comparison and alternative search intent. Facts about SlideViewer and CaseViewer were taken from 3DHISTECH's own pages on 8 October 2026:

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